Discuss your answer with formulae whenever possible.
I) A-Discuss in details how glucose oxidation is important for energy production in human RBCs. (5marks)
B-Enumerate chronic complication of D.M and comment on its pathogenesis. (5 marks)
C-Two pathways of pyruvate. (6 marks)
D-Function of pentose shunt. (3 marks)
II) A-Synthesis and function of glutathione. (4 marks)
B-Biotransformation of tryptophan to melatonin. (3 marks)
C-Metabolic inborn errors of branched chain amino acids. (4 marks)
D-Show how the body convert citrate to GABA. (3 marks)
E-Sources of ammonia (NH3). (3 marks)
F-Biosynthesis of creatine. (3 marks)
III) a-Role Of creatinine in the transport of long chain fatty acids trough inner mitochondrial membrane. (3 marks)
B-Lipotropic factors. (3 marks)
C-Function of HDL. (3 marks)
D-Transport of cholesterol. (3 marks)
E-Citrate is an obligatory intermediate in cytoplasmic FA synthesis. (3 marks)
F-Conversion of glucose to palmitate. (5 marks)
IV) A-Inhibitors of oxidative phosphorylation. (3 marks)
B-Enumerate five of trace elements and discuss two of them. (4 marks)
V) Outline the causes of the following inborn metabolic errors (4 marks)
A-Favism
B-Essential fructosuria
C-Primary hyperoxalurea
D-Homocystinuria.
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موضوع: امتحان البيو 2010 جامعه دمياط 